Clinical Trials Near me

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Find Clinical Trials Near Me | A Comprehensive Guide

Imagine this: your loved one has just been diagnosed with a rare disease, and you want to explore all possible treatment options. You’ve heard about clinical trials but don’t know where to start. This comprehensive guide will help you navigate the world of clinical trials, from finding “clinical trials near me” to understanding the different phases and the role of healthy volunteers. Together, we’ll delve into the impact of clinical trials on medical research and public health.

Key Takeaways

  • Discover ways to find local clinical trials, and understand the essential components of participation.

  • Learn about informed consent, eligibility criteria, interventional and observational studies for clinical trials.

  • Understand how healthy volunteers are needed in research and development to benefit public health outcomes.

Discovering Local Clinical Trials

Participate in a clinical trial near you by first understanding that participating in clinical trials is a critical step for advancing medical research and finding new treatments for various diseases.

This section delves into two primary ways to locate local clinical trials: through online databases and by liaising with local health care providers.

Online Databases for Clinical Trial Searches

Online databases are a valuable resource for finding clinical trials. One such database is, a searchable registry and results database of clinical studies conducted in the United States and around the world.

Another great resource is the NIH Clinical Center, a part of the National Institutes of Health, which hosts a variety of studies ranging from rare diseases to chronic health conditions and even opportunities for healthy volunteers.

To locate clinical trials at the NIH Clinical Center, follow these steps:

  1. Enter your diagnosis, sign, symptom, or other keywords linked to your condition.

  2. This will generate a list of suitable trials.

  3. Keep in mind that eligibility criteria for clinical trials may vary depending on the particular study, so it is important to review them before applying to participate.

Connecting with Local Health Care Providers

Health care providers play a vital role in local clinical trials, from providing information about available studies to monitoring patient progress during the trial. For liaising with local health care providers about clinical trials, maintain open and honest communication. Here are some steps to follow:

  1. Investigate local providers involved in clinical trials.

  2. Set up a meeting or phone call to express your interest in participation.

  3. Maintain open and honest communication throughout the process.

Prepare a list of questions to ask the provider about the trial, such as:

  • What is the purpose of the trial?

  • What are the potential risks and benefits?

  • What are the eligibility criteria?

  • How much time commitment is required?

Be ready to provide information about your medical history and any relevant health conditions. Don’t hesitate to express any concerns or reservations you may have and ask for clarification or additional information.

If you decide to participate, follow the provider’s instructions for enrollment and any necessary paperwork or consent forms.

Understanding Clinical Trial Participation

Before diving into the world of clinical trials, it’s essential to understand the importance of informed consent and eligibility criteria, as well as the differences between the two types of clinical trials: interventional and observational studies.

This section delves into these important aspects of taking part in clinical trials.

Informed Consent and Eligibility Criteria

Informed consent and eligibility criteria constitute key components of clinical trials. Informed consent ensures that participants fully understand the potential risks and benefits associated with a trial. To ensure you comprehend the risks and benefits, you should:

  1. Review the informed consent document

  2. Ask questions to the research team

  3. Obtain additional information from reliable sources

  4. Consult with your healthcare provider.

Eligibility criteria, on the other hand, are implemented to guarantee the safety and validity of a study. These criteria may include:

  • Age

  • Gender

  • Specific medical conditions or diseases

  • Stage of the disease

  • Previous treatments received

  • Overall health status

In contrast, exclusion criteria are factors that disqualify potential participants from the study to ensure the integrity of the research.

By establishing specific criteria, researchers can reduce potential risks and maximize the chances of obtaining precise and dependable results.

Types of Clinical Trials: Interventional and Observational Studies

Within clinical trials, research studies typically fall into two categories: interventional and observational. Interventional studies involve testing new treatments or interventions on participants, while observational studies focus on observing participants without administering any interventions.

Interventional studies are designed to test the safety and effectiveness of new treatments and interventions, such as drugs, medical devices, or lifestyle changes. Observational studies, on the other hand, aim to understand the causes and progression of diseases by examining patterns, causes, and effects of health and disease in specific groups of people.

The Role of Healthy Volunteers in Clinical Trials

Healthy volunteers play a critical role in clinical trials, providing essential data for researchers and helping them understand the effects of new treatments on healthy individuals.

This section examines the importance of healthy volunteers in clinical trials and outlines the steps to become one.

Why Healthy Volunteers Are Needed

Healthy volunteers are essential in clinical trials for several reasons. First, they provide a point of comparison for participants with health conditions, enabling researchers to determine the efficacy and safety of new treatments. Second, they allow researchers to evaluate potential side effects and risks of the treatment without the interference of pre-existing health conditions.

By participating in clinical trials, healthy volunteers contribute to the advancement of medical knowledge and the development of new medications and treatments, ultimately benefiting public health. Their involvement is paramount in furthering our understanding of diseases and the effectiveness of various treatments, as well as discovering the potential benefits of new interventions.

How to Become a Healthy Volunteer

To volunteer as a healthy participant in a clinical trial, you must fulfill the specific eligibility requirements of the study that interests you. To find clinical trials seeking healthy volunteers, you can search for trials on platforms such as:


  • Participate in Research



Once you find a clinical trial that interests you, follow the enrollment process, which typically involves a pre-screening process, such as a telephone interview or an online questionnaire.

It is important to note that participation in clinical trials is voluntary and may not be suitable for everyone. Be sure to consider the potential risks associated with being a healthy volunteer in clinical trials, such as side effects or adverse events.

Phases of Clinical Trials: From Safety to Effectiveness

Clinical trials progress through different phases, each with its own objectives and focus. This segment covers the various stages of clinical trials, from assessing safety and dosage in Phase I to evaluating effectiveness and comparisons in Phase III.

Phase I trials are designed to assess the safety of a drug or device. They involve a small

Phase I: Safety and Dosage

The primary focus of Phase I clinical trials is to assess the safety of a new treatment and establish the ideal dosage range. During this phase, researchers administer the treatment to a small group of healthy volunteers and monitor them for any adverse effects. The dosage is gradually increased until a maximum tolerated dose (MTD) is reached, which is the highest dose that can be administered without causing unacceptable levels of toxicity.

Phase I trials generally involve small sample sizes and can last several months, with most trials concluding within a year. The primary objective is to identify the highest safe and well-tolerated dose for further study in Phase II trials.

Phase II: Efficacy and Side Effects

Phase II clinical trials are designed to assess the efficacy and safety of a drug or treatment in a larger group of individuals with a given disease or condition. During this phase, researchers evaluate the treatment’s effectiveness in treating the specific condition and monitor participants for side effects. The data collected during Phase II trials helps determine the appropriate dosage and treatment regimen for further evaluation in Phase III trials.

Phase II clinical trials typically involve a larger group of participants, ranging from 100 to 300 individuals. These trials can last for several months to two years, depending on the nature of the treatment and the disease being studied.

Phase III: Effectiveness and Comparison

The primary objective of Phase III clinical trials is to evaluate the effectiveness of the experimental drug compared to existing treatments, as well as to assess its long-term safety and efficacy. During this phase, the new treatment is administered to a large group of patients with the specific disease or condition for which the drug is being developed.

Phase III trials directly compare the new treatment with the standard treatment in order to ascertain if the new treatment is more effective and/or has fewer side effects than the existing treatment. These trials typically range from 1 to 4 years in length and can involve hundreds or even thousands of participants.

The Impact of Clinical Trials on Medical Research and Public Health

Clinical trials, a crucial aspect of clinical research studies, have a profound impact on medical research and public health, as they lead to the development of new medications, treatments, and devices that improve patient outcomes and save lives. By participating in a clinical study, also known as clinical research trials, volunteers play a vital role in advancing medical knowledge.

This section delves into the effects of clinical trials on medical research and public health, with a focus on advancements in medicine and disease prevention.

Advancements in Medicine and Treatment Options

Clinical trials have led to a myriad of significant medical advancements, including:

  • The creation of mRNA vaccines

  • Organ repair using lab-grown cells

  • Enhanced diabetes treatments

  • Innovative pain management breakthroughs

These advances have transformed the way we approach patient care and have led to improved health outcomes for countless individuals.

Some notable treatments developed from clinical trials include a diabetes drug for Parkinson’s disease, ADC (Antibody-Drug Conjugate) for ovarian cancer, and innovative radiotherapy techniques for administering treatment. Additionally, clinical trials have played a crucial role in the development of new medical devices and digital health technologies, which have improved the quality and efficiency of clinical trials themselves.

Importance for Disease Prevention and Control

Clinical trials hold a significant place in disease prevention and control by investigating innovative methods of prevention, detection, and treatment. They provide valuable insights into diseases, their prevention, and the formulation of effective interventions.

Clinical trials have had a considerable impact on a variety of diseases, such as cancer, cardiovascular diseases, neurological disorders, and rare diseases. Through clinical trials, researchers have developed novel treatment options, more precise diagnostic techniques, and a deeper insight into disease mechanisms.

The advancements made through clinical trials have also impacted public health policy and practice, informing decisions and optimizing patient care.


In conclusion, clinical trials are essential for advancing medical research and improving public health. Whether you are considering participating in a clinical trial, seeking to become a healthy volunteer, or simply looking to understand the process, this comprehensive guide has provided you with valuable information on finding local clinical trials, understanding the different phases, and recognizing the impact of clinical trials on medical research and public health. By staying informed and engaged, you can contribute to the progress of scientific research that has the potential to save lives and treat diseases for generations to come.

Frequently Asked Questions

Where can I participate in a clinical trial?

You can find clinical trials around the nation and worldwide through, which is operated by NIH and offers trials for a range of diseases and conditions.

What clinical trials pay the most?

Clinical trials for investigational vaccines typically pay the most, particularly those in Phase I studies. For other medications, medical devices, and tests, higher-paying clinical trials may also be available.

How do I find clinical trials near me?

Discover clinical trials near you by using My LocalStudy’s Find a Study page or looking up studies on for more detailed information. Consult your health care professionals for advice about participating in a clinical study.

How much does a clinical trial cost?

The cost of a clinical trial can range anywhere from $100,000 to over $30 million, with an average of around $4 million for Phase 1 trials, $13 million for Phase 2, and $20 million for Phase 3. Pivotal (Phase 3) studies for new drugs approved by the FDA cost a median of $41,117 per patient.

What is the difference between interventional and observational studies?

Interventional studies involve administering interventions or treatments to participants, while observational studies observe participants without intervening.